Acrodermatitis Enteropathica

Also indexed as: Acrodermatitis Enteropathy, Zinc Malabsorption (Inherited)

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Acrodermatitis enteropathica is a rare inherited childhood disorder that results in the inability to absorb adequate amounts of zinc from the diet. Anyone who is severely zinc deficient can develop the same symptoms that occur in the inherited form of this disorder.

Symptoms of acrodermatitis enteropathica include skin lesions, hair loss, and diarrhea. If untreated, the condition can result in death during infancy or early childhood.

Checklist for Acrodermatitis Enteropathica

Rating	Nutritional Supplements	Herbs
	Zinc
Reliable and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support and/or minimal health benefit.

What are the symptoms of acrodermatitis enteropathica?

Symptoms of this condition include growth retardation, diarrhea, hair loss, and a red skin rash. Skin around the fingernails may be red and swollen.

Medical treatments

Individuals with acrodermatitis are usually given over the counter zinc supplements.

Dietary changes that may be helpful

Oysters, beef, liver, pumpkin seeds, pecans, and Brazil nuts are all high in zinc.¹ However, people with acrodermatitis enteropathica also need to take zinc supplements.

Nutritional supplements that may be helpful

Supplementation with zinc brings about complete remission in hereditary acrodermatitis enteropathica. Zinc supplements in the amount of 30 to 150 mg per day are used by people with this condition.² People with acrodermatitis enteropathica need to be monitored by a healthcare professional to ensure that their level of zinc supplementation is adequate and that the zinc supplements are not inducing a copper deficiency.

Are there any side effects or interactions?
Refer to the individual supplement for information about any side effects or interactions.

References

1. Murray MT. The Healing Power of Foods. Rocklin, CA: Prima Publishing, 1993, 7.

2. Berkow R. Merck Manual. Whitehouse Station, NJ: Merck Research Laboratories, 1987, 946.

The information presented in this website is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.